Factors associated with treatment modification during the first year of contemporary HAART
نویسندگان
چکیده
Methods We evaluated by logistic regression and Cox proportional model analysis factors associated to treatment modification during the first year of HAART in antiretroviral naïve patients from a single HIV unit in Madrid. Variables included in the analysis were: Basic sociodemographic characteristics, data on the clinical course, VHC coinfection, antiretroviral therapy and immunologic and virologic variables.
منابع مشابه
Modification of Initial Highly Active Antiretroviral Therapy (HAART) Regimen in Paediatric HIV Patients
Background Treatment options among Human Immunodeficiency Virus (HIV)-infected children are limited as only a few Highly Active Antiretroviral Therapy (HAART) are approved worldwide for paediatric use. Among children, frequent changes in HAART regimen can rapidly exhaust treatment options, and information addressing this issue is scarce. Objective The aim of the study was to determine factors...
متن کاملImpact of gender on response to highly active antiretroviral therapy in HIV-1 infected patients: a nationwide population-based cohort study
BACKGROUND Impact of gender on time to initiation, response to and risk of modification of highly active antiretroviral therapy (HAART) in HIV-1 infected individuals is still controversial. METHODS From a nationwide cohort of Danish HIV infected individuals we identified all heterosexually infected women (N=587) and heterosexually infected men (N=583) with no record of Hepatitis C infection d...
متن کاملPolyomavirus-Associated Progressive Multifocal Leukoencephalopathy (PML) in HAART era
Polyomaviruses may cause human disease, particularly in immunocompromised hosts. JCV, one of the members of polyomaviridae family, is the causative agent of the neurological disease progressive multifocal leukoencephalopathy (PML), which occurs mostly in immunocompromised patients. Progressive Multifocal leukoencephalopathy (PML) is a progressive demyelinating disorder of the central nervous sy...
متن کاملAntiretroviral treatment and quality of life in Africans living with HIV: 12-month follow-up in Burkina Faso
INTRODUCTION The scale-up of highly active antiretroviral therapy (HAART) has led to a significant improvement in survival of the HIV-positive patient but its effects on health-related quality of life (HRQOL) are less known and context-dependent. Our aim was to assess the temporal changes and factors associated with HRQOL among HIV-positive adults initiating HAART in Burkina Faso. METHODS HIV...
متن کاملInjection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohorts
BACKGROUND Sustained use of antiretroviral therapy has been consistently shown to be one of the primary predictors of long-term effectiveness. Switching and discontinuation reflect patient and provider decisions that may limit future treatment options. In this study, we utilize data reported at semi-annual study visits from three prospective cohort studies, the AIDS Link to IntraVenous Exposure...
متن کامل